Bruna Bellaver

Evaluation of harmonization methods to mitigate assay and cohort effects in plasma p-tau217

This study evaluates harmonization methods to reduce assay and cohort effects in plasma p-tau217 measurements across two cohorts, finding that quantile mapping is most effective.

Impact of cardiometabolic factors and blood beta-amyloid on the volume of white matter hyperintensities in dementia-free subjects with cognitive complaints

The paper examines the relationship between cardiometabolic factors, blood beta-amyloid, and white matter hyperintensities in dementia-free individuals with cognitive complaints, finding stronger associations with cardiometabolic markers.

Cross-species comparative hippocampal transcriptomics in Alzheimer's disease

This study compares hippocampal transcriptomics across AD mouse models and human patients, finding greater similarity between mouse models and late-onset AD.

Short-term consumption of ultra-processed semi-synthetic diets impairs the sense of smell and brain metabolism in mice

This study shows that short-term consumption of ultra-processed semi-synthetic diets impairs olfactory function and brain metabolism in mice.

Hippocampal GFAP-positive astrocyte responses to amyloid and tau pathologies

The paper investigates GFAP-positive astrocyte responses to amyloid-beta and tau pathologies in humans and mouse models, finding distinct molecular signatures associated with each pathology.