Thomas W. Buford

Molecular Transducers of Physical Activity Consortium (MoTrPAC): Initial Insights into the Dynamic Human Responses to Exercise

The paper presents initial findings from the MoTrPAC consortium, showing that acute and chronic exercise induce distinct physiological and molecular responses, with chronic training improving key health metrics.

The Long Non-coding RNA Landscape of Endurance Exercise Training

This study identifies tissue-specific lncRNA responses to endurance exercise in rats, revealing sex differences and potential therapeutic implications.

Multi-omic identification of key transcriptional regulatory programs during endurance exercise training in rats

The paper identifies tissue-specific transcriptional regulatory programs in rats undergoing endurance exercise training by integrating chromatin accessibility, DNA methylation, and gene expression data.

Aging amplifies a gut microbiota immunogenic signature linked to heightened inflammation

This study shows that aging alters gut microbiota immunogenicity, increasing TLR4 activation and inflammation, and that these changes are linked to heightened host inflammation.

Sexual dimorphism and the multi-omic response to exercise training in rat subcutaneous white adipose tissue

This study examines how endurance exercise training affects rat subcutaneous white adipose tissue, revealing sex-specific molecular responses and differences in adiposity and metabolism.

Temporal dynamics of the multi-omic response to endurance exercise training across tissues

This study profiles multi-omic changes in multiple tissues of rats during endurance exercise training, identifying molecular adaptations and sex-specific responses across time.