Author

Jinendiran Sekar

The Lundquist InstituteORCID 0000-0002-8044-1628Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Research Focus:host-pathogen & immune response· 3 Organism:mouse· 3 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Organism:human· 1

Frequent Co-Authors

Marc SwidergalliD· 3 shared Jian MiaoiD· 2 shared Nicholas Gregory JendzjowskyiD· 2 shared Nicolas MilletiD· 2 shared Norma V. SolisiD· 2 shared Scott G. FilleriD· 2 shared Aize PellóniD· 1 shared Amirhossein DavariiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 33 mutual co-author links

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3 shared papersImmunology

Marc SwidergallORCID

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Author profile →

4 papers

Recent·Most cited

Sympathetic neurons control adaptive immunity in response to Streptococcus pneumoniae infection by regulating T cell and B cell effector function

Fengli Zhu, Kayla Davis, Sreemoyee Acharya, Rishit Pattanashetti, Jinendiran Sekar, Diane Aguilar, Nathisha Kalpage, Omid Akbari, Srividya Swaminathan, Peter Jorth, Marc Swidergall, Nicholas Gregory Jendzjowsky

This study shows that sympathetic neurons regulate T cell and B cell responses to Streptococcus pneumoniae infection, enhancing IgG production and bacterial clearance.

bioRxiv · Sep 22, 2026 · PreprintImmunology

Inhibition of Candida albicans virulence factor by cyclic dipeptides derived from Aeromonas veronii V03

Jinendiran Sekar, Gokul Parasuraman, Anandakumar Shanmugam, Dhanasekaran Dharumadurai, B. S. Dileep Kumar, Natesan Sivakumar

This study identifies cyclic dipeptides from Aeromonas veronii V03 that inhibit Candida albicans virulence traits and show antibacterial activity.

Scientific Reports · Apr 11, 2026Peer-reviewedMicrobiology

Non-canonical IL-22 receptor signaling remodels the mucosal barrier during fungal immunosurveillance

Nicolas Millet, Jinendiran Sekar, Norma V. Solis, Jian Miao, Antoine Millet, Felix E.Y. Aggor, Asia S. Wildeman, Melissa Erin Cook, Amirhossein Davari, Brian M. Peters, Michail S. Lionakis, Sarah L. Gaffen, Nicholas Gregory Jendzjowsky, Scott G. Filler, Marc Swidergall

This study shows that fungal-induced immunosurveillance remodels the oral mucosal barrier via a non-canonical IL-22 receptor complex, enhancing resistance to Candida albicans colonization.

Nature Communications · Apr 3, 2026Peer-reviewedImmunology

Metabolic imprinting drives epithelial memory during mucosal fungal infection

Jinendiran Sekar, Norma V. Solis, Jian Miao, Nicolas Millet, Bryce Tom, Derek Quintanilla, Aize Pellón, David L. Moyes, Joseph A. Gogos, Harry B. Rossiter, Scott G. Filler, Mihai Gheorghe Netea, Jennifer K. Yee, Marc Swidergall

This study identifies a metabolic-epigenetic mechanism in oral epithelial cells that enhances protection against fungal infection through proline catabolism and mitochondrial function.

bioRxiv · Jul 11, 2025 · PreprintImmunology