Sui Huang

This study examines the dynamic interactions between nucleoli and centromeres in living cells, showing that centromeres move and associate with nucleoli during interphase, with these interactions dependent on rDNA transcription and nucleolar integrity.

The paper identifies a cold fibrotic network in LUSC TME driven by CAFs and shows its conservation in other CIACs, suggesting therapeutic targets.

The paper identifies a fibroblast state called STIF that drives YAP-dependent regenerative programs and (pre)malignancy through mechanotransduction in response to tissue injury.

The paper shows that RNA polymerase I co-regulates chromatin domains and mRNA synthesis with RNA polymerase II, affecting genome connectivity and gene expression.