Author

Karla Parra

The University of Texas Southwestern Medical CenterORCID 0000-0002-2408-6860Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Assay:imaging· 1 Organism:mouse· 1 Assay:proteomics· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Alice MazzagattiiD· 1 shared Andrea Woods· 1 shared Anthony J. DavisiD· 1 shared Collin GilbreathiD· 1 shared Ewa LangneriD· 1 shared Guy M. GeniniD· 1 shared Hani Y. SuleimaniD· 1 shared Jeffrey H. MineriD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperCancer Biology

Alice MazzagattiORCID

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2 papers

Recent·Most cited

Progressive Actomyosin Remodeling Defining a Structured Podocyte Injury Response in Nephrotic Syndrome

Ewa Langner, Karla Parra, Shumeng Jiang, Sanjay R. Jain, Moe R. Mahjoub, Guy M. Genin, Jeffrey H. Miner, Hani Y. Suleiman

This study identifies three sequential stages of actomyosin remodeling in podocyte injury across multiple kidney diseases, suggesting a structured, potentially reversible response.

bioRxiv · Oct 9, 2026 · PreprintCell Biology

Dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-mutant prostate cancer

Mia E. Hofstad, Andrea Woods, Karla Parra, Zoi E. Sychev, Alice Mazzagatti, Xiaofang Huo, Lan Yu, Collin Gilbreath, Wei‐Min Chen, Anthony J. Davis, Peter Ly, Justin M. Drake, Ralf Kittler

This study shows that dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-deficient prostate cancer cells, with Compound B effectively achieving this in vitro and in vivo.

Oncogene · Mar 21, 2025Peer-reviewedCancer Biology