Alice Mazzagatti

This study shows that dual inhibition of ATR and DNA-PKcs radiosensitizes ATM-deficient prostate cancer cells, with Compound B effectively achieving this in vitro and in vivo.

This study identifies TASOR's role in maintaining developmental potential during the transition from naive to primed pluripotency by preventing L1 transposable element activation and subsequent cell death.

The paper identifies DNA copy number alterations and chromosome-scale losses caused by replication stress in non-transformed cells, revealing their role in chromosomal instability and cancer evolution.