Author

Tuula E. Ritakari

UK Dementia Research InstituteORCID 0000-0002-2409-2929Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Assay:imaging· 1 Approach:statistical model· 1

Frequent Co-Authors

Alessandra Cardinalli· 1 shared Andrew Mark McIntoshiD· 1 shared Bhuvaneish Thangaraj SelvarajiD· 1 shared David StoryiD· 1 shared Evdokia PazaiD· 1 shared Heather Clare WhalleyiD· 1 shared James D. CooperiD· 1 shared Josef PrilleriD· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Alessandra Cardinalli

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2 papers

Recent·Most cited

Human induced pluripotent stem cell-derived microglia contribute to thepathophysiology of Fragile X syndrome via increased RAC1 signaling

Poulomi Banerjee, Shreya Das Sharma, Karen Burr, Kimberley J. Morris, Tuula E. Ritakari, Paul S. Baxter, James D. Cooper, Alessandra Cardinalli, Srividya Subash, Evdokia Paza, David Story, Sumantra Chattarji, Peter C. Kind, Neil O. Carragher, Bhuvaneish Thangaraj Selvaraj, , Siddharthan Chandran

This study shows that FMRP loss in microglia increases RAC1 signaling, leading to inflammation and neuronal hyperexcitability in FXS, which can be mitigated by RAC1 inhibition.

bioRxiv · Jun 24, 2024 · PreprintNeuroscience

White matter microstructure and its relation to longitudinal measures of depressive symptoms in mid-late life

Xueyi Shen, Mark J. Adams, Tuula E. Ritakari, Simon R. Cox, Andrew Mark McIntosh, Heather Clare Whalley

The paper examines the relationship between white matter microstructure and longitudinal depressive symptoms in mid-late life, finding significant associations across different measures of symptomatology.

Biological Psychiatry · Jun 22, 2019Peer-reviewedNeuroscience