Paul S. Baxter

The paper identifies NRF2 activation in mononuclear myeloid cells as a protective response to intracerebral haemorrhage, showing its therapeutic potential through modulation of interferon pathways.

This study shows astrocytes alter the transcriptomic and epigenetic landscape of developing cortical neurons, promoting intrinsic excitability and influencing disease-related pathways.

This study shows that FMRP loss in microglia increases RAC1 signaling, leading to inflammation and neuronal hyperexcitability in FXS, which can be mitigated by RAC1 inhibition.

This study shows superoxide enters neurons directly through LRRC8A-containing volume-regulated anion channels, blocking oxidative stress and glutamate excitotoxicity.

The paper shows human astrocytes and microglia ingest more synapses in Alzheimer's disease via MFG-E8, and inhibiting MFG-E8 reduces this ingestion in cultured cells.

The paper examines flight-freeze response imbalances in Nlgn3-/y rats, finding hyperexcitability in periaqueductal grey neurons linked to altered fear behaviors.

This study investigates synaptic function in a Cdkl5 KO rat model of CDKL5 deficiency disorder, finding normal NMDA and AMPA receptor function but altered synaptic density and plasticity.