The paper examines how salt stress affects chloroplast structure in guard cells of two faba bean genotypes and links these changes to ion distribution and photosynthetic performance.

bioRxiv · Aug 11, 2026 · PreprintPlant Biology

Metformin acts directly in the brain to slow features of neurodegeneration.

Edward C. Harding, Hsiao‐Jou Cortina Chen, Dmytro Shepilov, Marc Welzer, Viviana Macarelli, Alix Schwiening, Christine Rowley, Sanya Aggarwal, Dean Swinden, Deborah Kronenberg‐Versteeg, Florian T. Merkle

This study shows metformin can slow neurodegeneration features in mice, even in metabolically healthy individuals, by acting directly in the brain.

bioRxiv · Jul 18, 2023 · PreprintNeuroscience

A reference induced pluripotent stem cell line for large-scale collaborative studies

Caroline B. Pantazis, Andrian Yang, Erika Lara, Justin A. McDonough, Cornelis Blauwendraat, Lirong Peng, Hideyuki Oguro, Jitendra Kumar Kanaujiya, Jizhong Zou, David P. Sebesta, Gretchen Pratt, Erin Cross, Jeffrey Blockwick, Philip Buxton, Lauren Kinner-Bibeau, , Florian T. Merkle

The paper identifies and characterizes a reference iPSC line, KOLF2.1J, for standardized use in collaborative studies across multiple differentiation protocols and assays.

Cell stem cell · Dec 1, 2022Peer-reviewedNeuroscience