Author

Michael Krueger

Baylor College of MedicineORCID 0000-0002-2476-5505Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Research Focus:benchmarking· 1 Research Focus:deconvolution· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Hua‐Sheng ChiuiD· 2 shared Jessica L. EppsiD· 2 shared Mohammad Javad Najaf Panah· 2 shared Pavel SumaziniD· 2 shared Tsz‐Kwong ManiD· 2 shared Alexandra McLean StevensiD· 1 shared Barry Zorman· 1 shared Burkhard BecheriD· 1 shared

Activity by Year

2023-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 39 mutual co-author links

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2 shared papersCancer Biology

Hua‐Sheng ChiuORCID

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2 papers

Recent·Most cited

Characterization of Chemoresistant Cell Populations Improves Risk Stratification and Therapy Prediction in Pediatric AML

Mohammad Javad Najaf Panah, Alexandra McLean Stevens, Michael Krueger, Max P Rochette, Sohani K Sandhu, Lana E Kim, Hua‐Sheng Chiu, Jessica L. Epps, Sonal Somvanshi, Barry Zorman, María Rodríguez Martínez, Marianna Rapsomaniki, Susanne Unger, Burkhard Becher, Joanna S. Yi, , Pavel Sumazin

The paper identifies chemoresistant cell populations in pediatric AML that improve risk prediction and reveal therapeutic targets for high-risk patients.

bioRxiv · Sep 25, 2025 · PreprintCancer Biology

Effective methods for bulk RNA-Seq deconvolution using scnRNA-Seq transcriptomes

Francisco Avila Cobos, Mohammad Javad Najaf Panah, Jessica L. Epps, Xiaochen Long, Tsz‐Kwong Man, Hua‐Sheng Chiu, Elad Chomsky, Evgeny Kiner, Michael Krueger, Diego di Bernardo, Luis Filipe Voloch, Jan J. Molenaar, Sander R. van Hooff, Frank Westermann, Selina Jansky, , Pavel Sumazin

The paper evaluates deconvolution methods for bulk RNA-Seq using scnRNA-Seq data, identifies biases, and introduces SQUID, a method that outperforms others in predicting cell mixtures and identifying cancer subclones.

Genome biology · Aug 1, 2023Peer-reviewedSystems Biology