Author

Grace Khuu

The University of MelbourneORCID 0000-0002-2550-0605Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Signature Assays, Organisms & Methods

Click to filter · or open tag

Research Focus:cell signaling & trafficking· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Approach:experimental assay· 2 Assay:ATAC-seq· 1 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Organism:human· 1

Frequent Co-Authors

Louise UoselisiD· 2 shared Michael LazarouiD· 2 shared Thanh Ngoc NguyeniD· 2 shared Adam I. FogeliD· 1 shared Aisling M. RossiD· 1 shared Allan Shuai HuangiD· 1 shared Amar BalihodziciD· 1 shared Andreas StrasseriD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersCell Biology

Louise UoselisORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Pre-existing levels of pro-survival proteins and induction of BCL-XL dictate cell fate after p53 activation

Allan Shuai Huang, Elizabeth Lieschke, Pedro L. Baldoni, Annabella Thomas, Julia M. Marchingo, Lauren Whelan, Grace Khuu, Eddie La Marca, Michael J. G. Milevskiy, Aisling M. Ross, Timothy M. Johanson, Margaret A. Potts, Leonie Gibson, Vineet Vaibhav, Laura F. Dagley, , Andreas Strasser

The paper shows that pre-existing levels of pro-survival proteins and BCL-XL induction determine cell fate after p53 activation, with implications for cancer therapy.

bioRxiv · Jul 2, 2026 · PreprintCancer Biology

Reconstitution of BNIP3/NIX-mediated autophagy reveals two pathways and hierarchical flexibility of the initiation machinery

Elias Adriaenssens, Stefan Schaar, Annan SI Cook, Jan F. M. Stuke, Justyna Zofia Sawa-Makarska, Thanh Ngoc Nguyen, Xuefeng Ren, Martina Schuschnig, Julia Romanov, Grace Khuu, Louise Uoselis, Michael Lazarou, Gerhard Hummer, James H. Hurley, Sascha Martens

Nature Cell Biology · Jul 25, 2025Peer-reviewedCell Biology

Presynapses are mitophagy pit stops that prevent axon degeneration

Wai Kit Lam, Runa S. J. Lindblom, Bridget Milky, Paris Mazzachi, Marjan Hadian-Jazi, Catharina J. Küng, Grace Khuu, Louise Uoselis, Thanh Ngoc Nguyen, Marvin Skulsuppaisarn, Tahnee L. Saunders, Marlene F. Schmidt, Grant Dewson, Adam I. Fogel, Cédric Bardy, Michael Lazarou

The paper identifies presynapses as sites of mitophagy in neurons and shows their role in preventing axon degeneration when mitophagy is defective.

bioRxiv · Sep 9, 2024 · PreprintCell Biology