Author

Vineet Vaibhav

The University of Melbourne

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Biochemistry· 1 Cancer Biology· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 3 Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:drug response / drug discovery· 1

Frequent Co-Authors

Laura F. DagleyiD· 4 shared Ching‐Seng AngiD· 2 shared Gordon K. SmythiD· 2 shared Pedro L. BaldoniiD· 2 shared Timothy M. JohansoniD· 2 shared Toby A. DiteiD· 2 shared Abner Gonzalez Castro· 1 shared Aisling M. RossiD· 1 shared

Activity by Year

2025-2026 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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4 shared papersCancer Biology

Laura F. DagleyORCID

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

Pre-existing levels of pro-survival proteins and induction of BCL-XL dictate cell fate after p53 activation

Allan Shuai Huang, Elizabeth Lieschke, Pedro L. Baldoni, Annabella Thomas, Julia M. Marchingo, Lauren Whelan, Grace Khuu, Eddie La Marca, Michael J. G. Milevskiy, Aisling M. Ross, Timothy M. Johanson, Margaret A. Potts, Leonie Gibson, Vineet Vaibhav, Laura F. Dagley, , Andreas Strasser

The paper shows that pre-existing levels of pro-survival proteins and BCL-XL induction determine cell fate after p53 activation, with implications for cancer therapy.

bioRxiv · Jul 2, 2026 · PreprintCancer Biology

Global analysis of cancer cell responses to USP9X inhibition

Philipp Schenk, Shane M. Devine, Simon A. Cobbold, Niall D. Geoghegan, Elizabeth L. Kyran, Ching‐Seng Ang, Jack A Alexandrovics, Dale J. Calleja, Dylan H. Multari, Vineet Vaibhav, Bernadine G.C. Lu, Theresa Klemm, Laura F. Dagley, Kym N. Lowes, Nicholas A. Williamson, , David Komander

This study identifies WEHI-092, a USP9X inhibitor, and shows it arrests cancer cells in metaphase, suggesting USP9X inhibitors could be selective mitotic poisons.

The EMBO Journal · Apr 7, 2026Peer-reviewedCell Biology

Unconventional binding of Calmodulin to CHK2 kinase inhibits catalytic activity

Christopher R. Horne, Tingting Wang, Samuel N. Young, Toby A. Dite, Hunter G. Nyvall, Sushant Suresh, Katherine A. Davies, Abner Gonzalez Castro, Vineet Vaibhav, Lucy J. Mather, Laura F. Dagley, Matthew J. Belousoff, Gerard Manning, Anthony R. Means, John E. Burke, , James M. Murphy

The paper identifies an unconventional mechanism where Ca2+-CaM binds CHK2 kinase to inhibit its activity, contrasting with its typical role in promoting kinase activity.

Biochemical Journal · Sep 26, 2025Peer-reviewedBiochemistry

MORC2 phosphorylation fine tunes its DNA compaction activity

Winnie Tan, J.-G. Park, Hariprasad Venugopal, Jieqiong Lou, Prabavi Shayana Dias, Pedro L. Baldoni, Kyoung-Wook Moon, Toby A. Dite, Christine R. Keenan, Alexandra D. Gurzau, Joonyoung Lee, Timothy M. Johanson, Andrew P. Leis, Jumana M. Yousef, Vineet Vaibhav, , Shabih Shakeel

This study characterizes MORC2 phosphorylation's role in DNA compaction and chromatin remodelling, showing it regulates ATP hydrolysis and DNA binding.

Nature Communications · Jul 1, 2025Peer-reviewedMolecular Biology

Intersecting impact of CAG repeat and Huntingtin knockout in stem cell-derived cortical neurons

Jennifer T. Stocksdale, Matthew Joseph Leventhal, Stephanie Lam, Yuxin Xu, Yi Wang, Keona Q. Wang, Reuben Thomas, Zohreh Faghihmonzavi, Yogindra Raghav, Charlene Smith-Geater, Jie Wu, Ricardo Miramontes, Kanchan Sarda, Heather Johnston, Min‐Gyoung Shin, , Leslie Michels Thompson

This study compares the effects of HTT knockout and CAG repeat expansion in cortical neurons, identifying shared and distinct biological pathways involved in HD.

Neurobiology of Disease · Apr 19, 2025Peer-reviewedCell Biology