Author

Adam P. Ryan

University College DublinORCID 0000-0002-2593-2264Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:whole-genome sequencing· 2 Organism:C. elegans· 1 Research Focus:gene regulatory network inference· 1 Research Focus:genome assembly· 1 Organism:human· 1 Approach:statistical model· 1 Organism:yeast· 1

Frequent Co-Authors

Kenneth H. WolfeiD· 3 shared Bing ZhaiiD· 2 shared Florent MorioiD· 2 shared Geraldine ButleriD· 2 shared Jillian Scully· 2 shared Sean A. BerginiD· 2 shared Aisling Y. CoughlaniD· 1 shared Amelia E. BarberiD· 1 shared

Activity by Year

2019-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenomics

Kenneth H. WolfeORCID

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3 papers

Recent·Most cited

Small pangenome of Candida parapsilosis reflects overall low intraspecific diversity

Adam P. Ryan, Sean A. Bergin, Jillian Scully, Evelyn Zuniga‐Soto, Conor Hession, Amelia E. Barber, Emilia Gómez-Molero, Oliver Bader, Florent Morio, Bing Zhai, Kenneth H. Wolfe, Geraldine Butler

The paper defines the pangenome of 372 Candida parapsilosis isolates, revealing low genetic diversity and identifying gene content variations associated with nitrogen metabolism.

mBio · Aug 25, 2025Peer-reviewedGenomics

Resistance to miltefosine results from amplification of the RTA3 floppase or inactivation of flippases in Candida parapsilosis

Sean A. Bergin, Fang Zhao, Adam P. Ryan, Carolin A. Müller, Conrad A. Nieduszynski, Bing Zhai, Thierry Rolling, Tobias M. Hohl, Florent Morio, Jillian Scully, Kenneth H. Wolfe, Geraldine Butler

This study identifies that resistance to miltefosine in Candida parapsilosis arises from RTA3 gene amplification or flippase inactivation, altering plasma membrane lipid asymmetry.

bioRxiv · Dec 16, 2021 · PreprintGenomics

Tetrad analysis without tetrad dissection: Meiotic recombination and genomic diversity in the yeast Komagataella phaffii (Pichia pastoris)

Stephanie Braun‐Galleani, Julie A. Dias, Aisling Y. Coughlan, Adam P. Ryan, Kevin P. Byrne, Kenneth H. Wolfe

The paper sequenced K. phaffii isolates and analyzed meiotic recombination in a cross, finding lower recombination rates and centromere suppression compared to S. cerevisiae.

bioRxiv · Jul 16, 2019 · PreprintGenetics