Author

Reynand Jay Canoy

Centre National de la Recherche ScientifiqueORCID 0000-0002-2610-8103Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Cancer Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cancer & tumor microenvironment· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Organism:human· 1 Research Focus:metabolism & bioenergetics· 1 Assay:metabolomics· 1

Frequent Co-Authors

Antonin MarchaisiD· 1 shared Birgit GeoergeriD· 1 shared Catherine BrenneriD· 1 shared Daniela Dias‐PedrosoiD· 1 shared Guido KroemeriD· 1 shared Hong-Toan LaiiD· 1 shared Liuba MazzantiiD· 1 shared Maria Eugénia Marques Da CostaiD· 1 shared

Activity by Year

2026-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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1 shared paperCancer Biology

Antonin MarchaisORCID

Mutual co-authors in cluster

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1 paper

Recent·Most cited

Combined inhibition of AIF/CHCHD4 interaction and GLS1 to exploit metabolic vulnerabilities in pediatric osteosarcoma

Hong-Toan Lai, Tran Ngoc Anh Nguyen, Maria Eugénia Marques Da Costa, Romain Fernandes, Daniela Dias‐Pedroso, Sylvère Durand, Guido Kroemer, Reynand Jay Canoy, Liuba Mazzanti, Yegor S Vassetzky, Nathalie Gaspar, Antonin Marchais, Birgit Geoerger, Tâp Ha‐Duong, Catherine Brenner

This study identifies a metabolic vulnerability in osteosarcoma by combining AIF/CHCHD4 inhibition and GLS1 suppression, showing synergy between mitoxantrone and telaglenastat in vitro and in vivo.

bioRxiv · Apr 7, 2026 · PreprintCancer Biology