Author

Chenguang Yu

Scripps Research InstituteORCID 0000-0002-2650-3779Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:deep learning· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:host-pathogen & immune response· 1 Assay:proteomics· 1 Approach:statistical model· 1 Assay:structural biology· 1

Frequent Co-Authors

Anant GharpureiD· 1 shared Andrew B. WardiD· 1 shared Anil K. Gupta· 1 shared Anna LewickaiD· 1 shared Anne CooperiD· 1 shared Arlo J. LoutaniD· 1 shared Arnab K. ChatterjeeiD· 1 shared Calvin J. GordoniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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1 shared paperMicrobiology

Anant GharpureORCID

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2 papers

Recent·Most cited

MicrobiologyJournal of Biological ChemistryPeer-reviewedJul 6, 2026

Substrate and target selectivity of 4'-fluoroadenosine against viral and host polymerases

Simon M. Walker, Arlo J. Loutan, Egor P. Tchesnokov…·Matthias Götte

This study investigates the antiviral activity and mechanism of 4'-fluoroadenosine against viral and host polymerases, showing broad-spectrum inhibition and potential for drug development.

DOI 10.1016/j.jbc.2026.113316

structural biologyexperimental assay

𝕏 PostBluesky

BiochemistryNucleic Acids ResearchPeer-reviewedJun 5, 2025

Mechanistic Studies of Small Molecule Ligands Selective to RNA Single G Bulges

Shalakha Hegde, Sana Akhter, Zhichao Tang…·Jingxin Wang

This study identifies coumarin derivatives that selectively bind RNA single G bulges, revealing key structural features and using computational and experimental methods to guide rational ligand design.

6 citations

proteomicsdeep learning

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