Author
Karolinska InstitutetORCID 0000-0002-2679-6946Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Shunsuke Nishio, Han Wang, Luca Jovine
The paper reports structures and binding data showing how a sperm protein recognizes divergent egg coat components through conserved interaction geometry and asymmetric binding dynamics.
bioRxiv · Aug 1, 2026 · PreprintBiophysics
Alisia Fadini, Minhuan Li, Airlie J. McCoy, Suresh Banjara, Hiroki Okumura, Eve Napier, Pietro Fontana, Amir R. Khan, Luca Jovine, Thomas C. Terwilliger, Randy J. Read, Doeke R. Hekstra, Mohammed AlQuraishi
ROCKET refines AlphaFold2 predictions against crystallographic, cryo-EM and cryo-ET data by gradient descent on MSA cluster profiles, capturing loop flips and domain shifts without retraining.
Nature Methods · Apr 1, 2026Peer-reviewedBiophysics✦ In-depth digest
Suresh Banjara, Han Wang, Céline Schaeffer, Alena Stsiapanava, Sara Sandin, Marta Carroni, Hiroki Okumura, Luca Rampoldi, Linda Sandblad, Luca Jovine
The paper shows Uromodulin forms salt-dependent velcro-like sheets that interact with UPEC pili, revealing structural mechanisms for UTI protection.
bioRxiv · May 9, 2025 · PreprintBiophysics
Elisa Dioguardi, Alena Stsiapanava, Eileen Fahrenkamp, Ling Han, Daniele de Sanctis, José Inzunza, Luca Jovine
This study shows that an IE3-derived scFV blocks fertilization by binding ZP2 and determines the structural basis of this interaction, offering insights for non-hormonal immunocontraceptives.
Proceedings of the National Academy of Sciences · Apr 11, 2025Peer-reviewedBiophysics
Krista R. Gert, Karin Panser, Joachim M. Surm, Benjamin S. Steinmetz, Alexander Schleiffer, Luca Jovine, Yehu Moran, Fyodor A. Kondrashov, Andrea Pauli
The paper identifies specific amino acid residues and N-glycosylation patterns in Bouncer proteins that mediate species-specific sperm-egg compatibility between medaka and zebrafish.
Nature Communications · Jun 14, 2023Peer-reviewedDevelopmental Biology