Author

Thao H. Nguyen

Brigham and Women's HospitalORCID 0000-0002-2767-0528Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:differential expression· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Abed AlFatah MansouriD· 1 shared Aidan Aicher· 1 shared Alexis BriceiD· 1 shared Amanda J. RheeiD· 1 shared Ana Mendes Diniz· 1 shared Andreea ManoleiD· 1 shared Arlene H. SharpeiD· 1 shared Beate WinneriD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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1 shared paperNeuroscience

Abed AlFatah MansourORCID

Mutual co-authors in cluster

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2 papers

Recent·Most cited

Depletion of extracellular asparagine impairs self-reactive T cells and ameliorates autoimmunity in a murine model of multiple sclerosis

Peter Georgiev, Sheila E. Johnson, Kiran Kurmi, Song-Hua Hu, SeongJun Han, Dillon G. Patterson, Thao H. Nguyen, Linglin Huang, Dan Liang, Naomi Goldman, Thomas S. Conway, Hannah Creasey, Jared H. Rowe, Marcia C. Haigis, Arlene H. Sharpe

eLife · Jul 8, 2026Peer-reviewedImmunology

Reduced synaptic activity and dysregulated extracellular matrix pathways are common phenotypes in midbrain neurons derived from sporadic and mutation-associated Parkinson's disease patients

Shani Stern, Shong Lau, Andreea Manole, Idan Rosh, Menahem Percia, Ran Ben Ezer, Maxim Nikolaievich Shokhirev, Fan Qiu, Simon T. Schafer, Abed AlFatah Mansour, Tchelet Stern, Pola Ofer, Yam Stern, Ana Mendes Diniz, Lynne Randolph Moore, , Fred H. Gage

The paper compares midbrain neurons from PD patients with mutations and sporadic PD, finding reduced synaptic activity and dysregulated extracellular matrix pathways as common features.

bioRxiv · Dec 31, 2021 · PreprintNeuroscience