Hayley A. Bounds

Network influence determines the impact of cortical ensembles on stimulus detection

The paper shows that network activity, not individual neuron sensitivity, determines the impact of cortical ensembles on stimulus detection in mice.

Balanced bidirectional optogenetics reveals the causal impact of cortical temporal dynamics in sensory perception

The paper develops balanced bidirectional optogenetics to alter neural temporal dynamics without affecting mean activity, showing that cortical temporal dynamics are causally required for sensory perception.

The logic of recurrent circuits in the primary visual cortex

The paper investigates how recurrent circuits in the primary visual cortex influence visual perception by analyzing the spatial arrangement and feature preferences of neuronal ensembles.

Modeling the Diverse Effects of Divisive Normalization on Noise Correlations

The paper introduces a statistical model of divisive normalization's effects on noise correlations in neural populations and validates it using mouse visual cortex data.

Dissociating instructive from permissive roles of brain circuits with reversible neural activity manipulations

This study uses optogenetic manipulations to distinguish instructive from permissive roles of brain circuits in visual detection, showing that midbrain regions can compensate for primary visual cortex loss.

High performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks

This paper engineers high-performance microbial opsins for precise spatial and temporal control of neuronal networks, enabling large-scale activation of defined neurons in vivo and in vitro.

All-optical recreation of naturalistic neural activity with a multifunctional transgenic reporter mouse

The paper introduces a multifunctional transgenic mouse line and a pipeline to read and write neural activity patterns with high precision in behaving animals.