William D. Hendricks

Feature-tuned synaptic inputs to somatostatin interneurons drive context-dependent processing

The paper identifies a recurrent circuit between pyramidal cells and somatostatin interneurons in mouse V1 that mediates context-dependent figure/ground modulation.

The logic of recurrent circuits in the primary visual cortex

The paper investigates how recurrent circuits in the primary visual cortex influence visual perception by analyzing the spatial arrangement and feature preferences of neuronal ensembles.

High performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks

This paper engineers high-performance microbial opsins for precise spatial and temporal control of neuronal networks, enabling large-scale activation of defined neurons in vivo and in vitro.

All-optical recreation of naturalistic neural activity with a multifunctional transgenic reporter mouse

The paper introduces a multifunctional transgenic mouse line and a pipeline to read and write neural activity patterns with high precision in behaving animals.

Exercise-induced enhancement of synaptic functiontriggered by the inverse BAR protein, Mtss1L.

Exercise increases hippocampal synaptic function through activity-dependent expression of Mtss1L, a BAR protein that promotes dendritic spine formation.

Early detonation by sprouted mossy fibers enables aberrant dentate network activity

The paper shows that sprouted mossy fibers in temporal lobe epilepsy can initiate recurrent network activity despite short-term depression due to high initial glutamate release and lack of adenosine inhibition.