Ian Antón Oldenburg

Design Tradeoffs in High Resolution, Large Field-of-View 3D All-Optical Control of Neural Circuits

The paper explores tradeoffs between resolution and field of view in scanless temporally focused holographic optogenetic systems, demonstrating improved spatial control using high NA objectives.

A nonlinear inhibition pathway underlying cortical responses to tuned holographic optogenetic perturbations

The paper develops a nonlinear theory to predict cortical responses to optogenetic perturbations and identifies a feature-tuned inhibition pathway involving SST interneurons.

The Importance of Synchrony in the Neural Control of Movement

This study shows that neural synchrony, not firing rate, is critical for movement generation by stimulating a small number of motor cortex neurons.

Circuit-Based Understanding of Fine Spatial Scale Clustering of Orientation Tuning in Mouse Visual Cortex

The paper investigates spatial organization of orientation tuning in mouse visual cortex and identifies micro-clustered organization of orientation preference.

The logic of recurrent circuits in the primary visual cortex

The paper investigates how recurrent circuits in the primary visual cortex influence visual perception by analyzing the spatial arrangement and feature preferences of neuronal ensembles.

High performance microbial opsins for spatially and temporally precise perturbations of large neuronal networks

This paper engineers high-performance microbial opsins for precise spatial and temporal control of neuronal networks, enabling large-scale activation of defined neurons in vivo and in vitro.

All-optical recreation of naturalistic neural activity with a multifunctional transgenic reporter mouse

The paper introduces a multifunctional transgenic mouse line and a pipeline to read and write neural activity patterns with high precision in behaving animals.

Spatial integration during active tactile sensation drives elementary shape perception

This study investigates how mice use active whisker touch to discriminate surface orientations, showing spatial integration in the barrel cortex is essential for this task.

Dynamically controlled light delivery over large brain volumes through tapered optical fibers

This paper introduces tapered optical fibers for dynamic light delivery in brain regions, showing they can illuminate large volumes or specific subregions with adjustable precision.