Author

Ragini Medhi

University of CambridgeORCID 0000-0002-2780-0708Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Molecular Biology· 2 Genomics· 1

Signature Assays, Organisms & Methods

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Research Focus:differential expression· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:C. elegans· 1 Research Focus:cell type annotation· 1 Organism:mouse· 1

Frequent Co-Authors

Eric Alexander MiskaiD· 3 shared Giulia FurlaniD· 2 shared Guillermo E. ParadaiD· 2 shared Martin HembergiD· 2 shared Ahmet Can BerkyurekiD· 1 shared Alexandra SapetschnigiD· 1 shared Alper AkayiD· 1 shared Amena NabihiD· 1 shared

Activity by Year

2017-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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3 shared papersMolecular Biology

Eric Alexander MiskaORCID

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3 papers

Recent·Most cited

Alternative splicing modulation by G-quadruplexes

Ilias Georgakopoulos‐Soares, Guillermo E. Parada, Hei Yuen Wong, Ragini Medhi, Giulia Furlan, Roberto Munita, Eric Alexander Miska, Chun Kit Kwok, Martin Hemberg

The paper identifies G-quadruplex motifs enriched near splice junctions and shows their involvement in alternative splicing in neuronal cells.

Nature Communications · May 3, 2022Peer-reviewedGenomics

RNA uridyl transferases TUT4/7 differentially regulate miRNA variants depending on the cancer cell-type

Ragini Medhi, Jonathan L. Price, Giulia Furlan, Beronia Gorges, Alexandra Sapetschnig, Eric Alexander Miska

This study shows that TUT4/7 regulate miRNA variants in a cell-type-specific manner, affecting cancer cell properties and miRNA-mRNA networks.

RNA · Dec 23, 2021Peer-reviewedMolecular Biology

The Aquarius/EMB-4 helicase licenses co-transcriptional gene silencing

Alper Akay, Tomás Di Domenico, Kin Man Suen, Amena Nabih, Guillermo E. Parada, Mark Larance, Ragini Medhi, Ahmet Can Berkyurek, Xinlian Zhang, Christopher J. Wedeles, Konrad L M Rudolph, Jan Engelhardt, Martin Hemberg, Ping Ma, Angus I. Lamond, , Eric Alexander Miska

This study identifies the Aquarius/EMB-4 helicase as essential for initiating small RNA-induced co-transcriptional gene silencing in C. elegans by facilitating HRDE-1 complex engagement with nascent transcripts.

Developmental Cell · Aug 1, 2017Peer-reviewedMolecular Biology