W. Robert Shaw

OocystMeter, a machine-learning algorithm to count and measure Plasmodium oocysts, reveals clustering patterns in the Anopheles midgut

OocystMeter automates oocyst counting and sizing in mosquito midguts, revealing clustered spatial patterns in malaria infections.

Additional blood meals increase mosquito infectivity by accelerating the transcriptional development of Plasmodium sporozoites

The paper shows that additional blood meals increase Plasmodium falciparum sporozoite infectivity to hepatocytes by altering their transcriptional profiles.

JNK signaling regulates reproductive trade-offs after Plasmodium infection in the malaria mosquito

This study shows that JNK signaling in Anopheles gambiae reduces reproductive investment and survival after Plasmodium infection by suppressing ecdysteroid production.

Lachesin is a mosquito receptor for multiple arthritogenic alphaviruses

This study identifies Lachesin as a mosquito receptor for multiple arthritogenic alphaviruses using CRISPR screening in Aedes albopictus cells.

Mapping Plasmodium transitions and interactions in the Anopheles female

This study uses single-cell RNA sequencing to map Plasmodium transitions and interactions in Anopheles mosquitoes, identifying key molecular processes and potential targets for transmission-blocking strategies.

CRISPR-mediated germline mutagenesis for genetic sterilization of Anopheles gambiae males.

This paper develops a CRISPR-based genetic sterilization system for Anopheles gambiae males, achieving high infertility rates and population suppression in competition cages.