Author

Sarah Guimbal

InsermORCID 0000-0002-2862-7679Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Assay:bulk RNA-seq· 1 Organism:human· 1

Frequent Co-Authors

Aïssata Diop· 1 shared Alain‐Pierre GadeauiD· 1 shared Alice AbélanetiD· 1 shared Britta EngelhardtiD· 1 shared Candice ChapoulyiD· 1 shared Casper G. SchalkwijkiD· 1 shared Eline BerendsiD· 1 shared Isa Frijns· 1 shared

Activity by Year

2020-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Aïssata Diop

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2 papers

Recent·Most cited

Extracellular methylglyoxal; the passage across brain endothelial cells and the effect on barrier function

Eline Berends, Sarah Guimbal, Xiaodi Zhang, Isa Frijns, Marjo P. H. van de Waarenburg, Jean L.J.M. Scheijen, Kristiaan Wouters, Robert J. van Oostenbrugge, Britta Engelhardt, Casper G. Schalkwijk, Sébastien Foulquier

This study investigates whether methylglyoxal (MGO) crosses the blood-brain barrier (BBB) in vivo and affects BBB permeability in vitro, finding no significant MGO passage or barrier disruption.

bioRxiv · Feb 20, 2026 · PreprintNeuroscience

Genetic disruption of the Blood Brain Barrier leads to protective barrier formation at the Glia Limitans

Pierre Mora, Pierre-Louis Hollier, Sarah Guimbal, Alice Abélanet, Aïssata Diop, Lauriane Cornuault, Thierry Couffinhal, Sam H. Horng, Alain‐Pierre Gadeau, Marie‐Ange Renault, Candice Chapouly

This study shows that BBB disruption triggers a secondary barrier at the Glia Limitans via astrocytic response, reducing disease severity in multiple sclerosis.

PLoS Biology · Nov 30, 2020Peer-reviewedNeuroscience