Roger Volden

The paper identifies distinct transcriptional programs in Ewing sarcoma driven by EWS::FLI1 fusions and shows their variability across tumors and cell lines.

The paper develops FLAIR2 to detect haplotype-specific transcript variation using long-read sequencing, revealing ADAR's role in splicing and RNA editing in lung cancer.

Mandalorion v4 improves isoform identification and quantification from full-length transcriptome sequencing data, showing high precision and recall even without genome annotation.

The paper uses R2C2 to sequence full-length cDNA from PBMCs, enabling isoform-level transcriptomes and TCR/BCR sequencing without Illumina data.

The paper uses full-length cDNA sequencing to accurately characterize the human immune cell transcriptome, enabling HLA allele typing and adaptive immune receptor repertoire analysis.

The paper depletes hemoglobin transcripts using Long-DASH to improve transcriptome annotation in polar bears, discovering 6,000 high-confidence isoforms and novel genes.

R2C2 improves nanopore read accuracy for full-length single-cell cDNA sequencing, enabling more accurate isoform-level transcriptome analysis.