Yingxin Ma

High plasticity of ribosomal DNA organization in budding yeast

This study constructs synthetic rDNA arrays in budding yeast and shows that reducing copy numbers or dispersing arrays does not harm cell growth or transcriptomes.

Large-scale genomic rearrangements boost SCRaMbLE in Saccharomyces cerevisiae

This study demonstrates that genomic rearrangements in yeast can be efficiently induced using SCRaMbLE, leading to diverse genetic changes and phenotypic effects.

Telomere-to-telomere genome of the model plant Physcomitrium patens

The paper presents a telomere-to-telomere genome assembly for Physcomitrium patens, correcting previous incomplete and erroneous regions and providing resources for moss genomics.

Reconstruct a eukaryotic chromosome arm by de novo design and synthesis

This paper designs and synthesizes a functional neochromosome in yeast that replaces a native chromosome arm, demonstrating genome plasticity and synthetic chromosome viability.