Author

Christina Seitz

Karolinska InstitutetORCID 0009-0004-9475-3229Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:bulk RNA-seq· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:variant calling· 1 Assay:whole-genome sequencing· 1

Frequent Co-Authors

Angela SimeoneiD· 1 shared Björn EvertssoniD· 1 shared Caroline IngreiD· 1 shared Chandana Rao Prakash· 1 shared Chiara Starvaggi CucuzzaiD· 1 shared Cillian NolaniD· 1 shared Daisuke KitamuraiD· 1 shared Eric Peter TheliniD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperNeuroscience

Angela SimeoneORCID

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2 papers

Recent·Most cited

Advancing Neurological Liquid Biopsy via Six-Base Sequencing of Cerebrospinal Fluid Cell-Free DNA

Chiara Starvaggi Cucuzza, Chandana Rao Prakash, Cillian Nolan, Mohammad Hossein Sepehri, Angela Simeone, Luke A. Sarre, Tom Charlesworth, Fabio Puddu, Yanan Han, Mohsen Khademi, Virginija Danylaité Karrenbauer, Björn Evertsson, Katharina Fink, Per Svenningsson, Caroline Ingre, , Maja Jagodic

This paper uses 6-base sequencing to analyze DNA modifications in cerebrospinal fluid cell-free DNA, providing insights into neurodegenerative biology for liquid biopsy applications.

bioRxiv · Sep 13, 2026 · PreprintNeuroscience

AID facilitates TET2 demethylation of Irf4 for plasma cell fate in germinal center B cells

Minghui He, Roberta D’Aulerio, Lia Gonçalves Pinho, Evangelos Doukoumopoulos, Tracer Yong, Rhaissa Calixto Vieira, Mariana M. S. Oliveira, Rômulo Gonçalves Agostinho Galvani, Saikiran K. Sedimbi, Christina Seitz, Nikolai V. Kuznetsov, María A. Zuriaga, Daisuke Kitamura, José J. Fuster, Vinı́cius Cotta-de-Almeida, , Lisa S. Westerberg

This study shows AID deficiency in B cells leads to reduced IRF4 expression and impaired plasma cell differentiation due to disrupted TET2-mediated demethylation of the Irf4 promoter.

bioRxiv · May 2, 2025 · PreprintImmunology