Author

Natalie K. Ryan

South Australian Health and Medical Research Institute

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Bioinformatics· 1 Cancer Biology· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 3 Assay:bulk RNA-seq· 2 Approach:experimental assay· 2 Assay:spatial transcriptomics· 2 Approach:benchmark study· 1 Research Focus:benchmarking· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

Lisa M. ButleriD· 3 shared Jasmine PlummeriD· 2 shared Kellie WiseiD· 2 shared Kirk B. JenseniD· 2 shared Luciano Gastón MartelottoiD· 2 shared Adam SharpiD· 1 shared Ayesha A. ShafiiD· 1 shared Azucena SalasiD· 1 shared

Activity by Year

2023-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 26 mutual co-author links

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3 shared papersCancer Biology

Lisa M. ButlerORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

AR coactivators, CBP/p300, are critical mediators of DNA repair in prostate cancer

Sumaira Sardar, Christopher M. McNair, Lakshmi Ravindranath, Saswati N. Chand, Wei Yuan, Denisa Bogdan, Jon C. Welti, Adam Sharp, Natalie K. Ryan, Liam A Knudsen, Matthew Joseph Schiewer, Elise G. DeArment, Thomas Janas, Xiaofeng A. Su, Lisa M. Butler, , Ayesha A. Shafi

This study identifies CBP/p300 as critical for DNA repair in prostate cancer and shows that targeting it enhances therapeutic response.

Oncogene · Sep 12, 2024Peer-reviewedCancer Biology

FixNCut: Single-cell genomics through reversible tissue fixation and dissociation

Laura Jiménez-Gracia, Doménica Marchese, Juan Camilo Nieto, Ginevra Caratù, Elisa Melón-Ardanaz, Victòria Gudiño, Sara Roth, Kellie Wise, Natalie K. Ryan, Kirk B. Jensen, Xavier Hernando‐Momblona, Joana P. Bernardes, Florian Tran, Laura Katharina Sievers, Stefan Schreiber, , Luciano Gastón Martelotto

FixNCut is a reversible fixation and dissociation method that preserves RNA integrity and cellular composition in human and mouse tissues, enabling robust single-cell and spatial analyses.

Genome biology · Mar 29, 2024Peer-reviewedBioinformatics

A Comparative Analysis of Imaging-Based Spatial Transcriptomics Platforms

David P. Cook, Kirk B. Jensen, Kellie Wise, Michael J. Roach, Felipe Segato Dezem, Natalie K. Ryan, Michel Zamojski, Ioannis S. Vlachos, Simon Knott, Lisa M. Butler, Jeffrey L. Wrana, Nicholas E. Banovich, Jasmine Plummer, Luciano Gastón Martelotto

Head-to-head on serial prostate adenocarcinoma sections: Xenium gave higher sensitivity, wider dynamic range and closer agreement with snRNA-seq; CosMx segmented cells better out of the box.

bioRxiv · Dec 13, 2023 · PreprintGenomics