Author

Stephan Lawrence Marguet

University of CologneORCID 0000-0002-3027-3136Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Assay:electronic health records· 2 Organism:mouse· 2 Research Focus:cell type annotation· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

Dirk IsbrandtiD· 2 shared Anja UrbachiD· 1 shared Birgit EngelandiD· 1 shared Christian Andreas HübneriD· 1 shared Christiane FrahmiD· 1 shared Chuanqiang ZhangiD· 1 shared Daniil KirianoviD· 1 shared Daria SavitskaiD· 1 shared

Activity by Year

2021-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 25 mutual co-author links

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2 shared papersNeuroscience

Dirk IsbrandtORCID

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2 papers

Recent·Most cited

Early postnatal CA3 hyperexcitability drives hippocampal development and epileptogenesis in SCN2A developmental and epileptic encephalopathy

Yana Reva, Katharina Ulrich, Xian Xin, Yuanyuan Liu, Michaela Barboni, Daniil Kirianov, Nima Mojtahedi, Sarah Schoeb, Hanna Oelßner, Daria Savitska, Mohamad Samehni, Francesca Xompero, Eva Schulze, Heinz Beck, Fabio Morellini, , Dirk Isbrandt

This study shows that early postnatal CA3 hyperexcitability drives hippocampal development and epileptogenesis in SCN2A-DEE, suggesting it as a therapeutic target.

bioRxiv · Jun 29, 2025 · PreprintNeuroscience

Intraneuronal chloride accumulation via NKCC1 is not essential for hippocampal network development in vivo

Jürgen Graf, Chuanqiang Zhang, Stephan Lawrence Marguet, Tanja Herrmann, Tom Floßmann, Robin Hinsch, Vahid Rahmati, Madlen Guenther, Christiane Frahm, Anja Urbach, Ricardo M. Neves, Otto Wilhelm Witte, Stefan J. Kiebel, Dirk Isbrandt, Christian Andreas Hübner, , Knut Kirmse

This study shows that NKCC1 deletion in developing mice has minimal impact on hippocampal network development and behavior, challenging its essential role in these processes.

Proceedings of the National Academy of Sciences · Mar 29, 2021Peer-reviewedNeuroscience