Author
Dartmouth CollegeORCID 0000-0002-3056-8356Unclaimed ORCID profile · follow to get notified of new preprints
5 papers
Recent·Most cited
Emile Létourneau, Océane Goncalves, Jean‐Philippe Côté, Fabrice Jean-Pierre
This study shows that elexacaftor/tezacaftor/ivacaftor (ETI) reduces biofilm formation and small colony variants in Pseudomonas aeruginosa PA14 grown in a CF lung model.
Lily A. Charpentier, Roxanna Barnaby, Carolyn Roche…·Bruce A. Stanton
This paper shows polymicrobial extracellular vesicles enhance virulence and inflammation in CF bronchial epithelial cells, and modulator therapy ETI does not reverse this effect.
Bassam El Hafi, Fabrice Jean-Pierre, George A. O’Toole
This study identifies a cross-feeding mechanism between Pseudomonas aeruginosa and Prevotella melaninogenica in a CF lung polymicrobial community, where metabolites from mucin degradation support P. melaninogenica survival.
Stacie E. Stuut, Dallas L. Mould, Fabrice Jean-Pierre, Deborah A. Hogan
This study shows Pseudomonas aeruginosa consumes nitrate in oxic conditions, requiring Dnr and Dnr-regulated NorCB for detoxification, despite no growth advantage from nitrate.
Rendi R. Rogers, Christopher A. Kesthely, Fabrice Jean-Pierre…·George A. O’Toole
The paper identifies Dpr-mediated H2O2 resistance as critical for Streptococcus sanguinis survival in a polymicrobial CF airway model.