Ribosomal modification by BUD23 drives selective translational control over energy state and metabolic health
Noelia Martínez‐Sánchez, Anneke Brümmer, Nichola J. Barron, Maria Voronkov, Daniel B. Rosoff, Angélica Liechti, Edward A. Hayter, Sébastien Chamois, René Dreos, Nicolas Guex, Elspeth M. Johnson, Matthew D. Baxter, Kerri L. M. Smith, Rebecca C Northeast, Gina L. J. Galli, , David A. Bechtold
This study identifies BUD23 as a regulator of energy homeostasis by controlling translation of mitochondrial and lipogenic mRNAs, linking ribosomal modification to metabolic health.
bioRxiv · May 16, 2025 · PreprintCell Biology