Charlotte Leese

The paper shows that SP-BOT induces two phases of pain relief in inflammatory arthritis, with long-term effects mediated by endogenous opioids.

This study evaluates three potential treatments for cancer-induced bone pain in mice, finding that dual inhibition of NGF and TNF significantly reduces pain-related behaviors.

This study shows that a single injection of SP-BOT provides long-term pain relief in a neuropathic pain model, with effects lasting up to 120 days and reversible with a second injection.