Author

Juan Pablo Cata

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-3156-1682Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Neuroscience· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:drug response / drug discovery· 1 Assay:electronic health records· 1 Organism:human· 1 Organism:mouse· 1

Frequent Co-Authors

Ali Bin SaifullahiD· 1 shared Changqun Yao· 1 shared Claudio Esteves TatsuiiD· 1 shared De‐Pei LiiD· 1 shared Francisco A. BlancoiD· 1 shared German Corrales· 1 shared Juliet M. MwirigiiD· 1 shared Kimberley F. ToliasiD· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperNeuroscience

Ali Bin SaifullahORCID

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2 papers

Recent·Most cited

MNK inhibitor eFT508 (Tomivosertib) suppresses ectopic activity in human dorsal root ganglion neurons from dermatomes with radicular neuropathic pain

Yan Li, Megan L. Uhelski, Robert Y. North, Juliet M. Mwirigi, Claudio Esteves Tatsui, Juan Pablo Cata, German Corrales, Theodore John Price, Patrick M. Dougherty

The paper shows that MNK inhibitor eFT508 reduces spontaneous activity in human DRG neurons from painful dermatomes.

bioRxiv · Jun 13, 2023 · PreprintNeuroscience

Tiam1-mediated synaptic plasticity drives comorbid depressive symptoms in chronic pain

Qin Ru, Yungang Lu, Ali Bin Saifullah, Francisco A. Blanco, Changqun Yao, Juan Pablo Cata, De‐Pei Li, Kimberley F. Tolias, Lingyong Li

This study identifies Tiam1-mediated synaptic plasticity in the ACC as a driver of depressive symptoms in chronic pain and shows that ketamine's antidepressant effects are mediated by blocking this pathway.

bioRxiv · Oct 15, 2021 · PreprintNeuroscience