Author
The University of Texas MD Anderson Cancer CenterORCID 0000-0003-3587-3103Unclaimed ORCID profile · follow to get notified of new preprints
6 papers
Recent·Most cited
Shamsuddin A. Bhuiyan, Saad S. Nagi, Ishwarya Sankaranarayanan…·NIH PRECISION Human Pain Network
This paper constructs a human dorsal root ganglion reference atlas, identifying 22 neuronal subtypes and 10 non-neuronal cell types, and reveals functional differences between human and mouse DRG neurons.
Megan L. Uhelski, Mandee K. Schaub, Felipe Espinosa…·Patrick M. Dougherty
This study examines suzetrigine's effects on human dorsal root ganglion neurons, showing it suppresses spontaneous pain-related discharges but requires longer exposure to affect evoked pain.
Juliet M. Mwirigi, Ishwarya Sankaranarayanan, Diana Tavares‐Ferreira…·Theodore John Price
The paper shows OSM-OSMR signaling via MAPKs drives transcriptomic changes in human DRG linked to neuropathic pain.
Yan Li, Megan L. Uhelski, Robert Y. North…·Patrick M. Dougherty
The paper shows that MNK inhibitor eFT508 reduces spontaneous activity in human DRG neurons from painful dermatomes.
Pradipta R. Ray, Stephanie I. Shiers, Diana Tavares‐Ferreira…·Theodore John Price
The paper profiles RNA in human DRGs from neuropathic pain patients, identifying sex-specific gene expression differences and neuro-immune pathways associated with pain.
Stephanie I. Shiers, Pradipta R. Ray, Andi Wangzhou…·Theodore John Price
The paper shows that human dorsal root ganglion neurons express ACE2, suggesting they may be a target for SARS-CoV-2 entry into the nervous system.