Author

Fabien Aubé

Lyon 1 UniversitéORCID 0000-0002-3184-0569Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Approach:experimental assay· 1 Organism:mouse· 1 Research Focus:spatial domain detection· 1

Frequent Co-Authors

Didier AuboeufiD· 3 shared Laurent ModoloiD· 3 shared Nicolas Fontrodona· 3 shared Cyril F. BourgeoisiD· 2 shared Franck MortreuxiD· 2 shared Hélène PolvècheiD· 2 shared Jean‐Baptiste ClaudeiD· 2 shared Sébastien LemaireiD· 2 shared

Activity by Year

2019-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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3 shared papersGenomics

Didier AuboeufORCID

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3 papers

Recent·Most cited

Translation-dependent and independent mRNA decay occur through mutually exclusive pathways that are defined by ribosome density during T Cell activation.

Blandine C. Mercier, Emmanuel Labaronne, David Cluet, Laura Guiguettaz, Nicolas Fontrodona, Alicia A. Bicknell, Antoine Corbin, Mélanie Wencker, Fabien Aubé, Laurent Modolo, Karina Jouravleva, Didier Auboeuf, Melissa J. Moore, Emiliano P. Ricci

The paper shows that mRNA decay during T cell activation occurs through translation-dependent and independent pathways, with ribosome density determining the pathway used.

Genome Research · Mar 20, 2024Peer-reviewedGenomics

Interplay between coding and exonic splicing regulatory sequences

Nicolas Fontrodona, Fabien Aubé, Jean‐Baptiste Claude, Hélène Polvèche, Sébastien Lemaire, Léon-Charles Tranchevent, Laurent Modolo, Franck Mortreux, Cyril F. Bourgeois, Didier Auboeuf

The paper shows that exons regulated by the same splicing factor share similar nucleotide composition and code for amino acids with similar physicochemical properties.

Genome Research · May 1, 2019Peer-reviewedGenomics

Interplay between gene nucleotide composition bias and splicing

Sébastien Lemaire, Nicolas Fontrodona, Jean‐Baptiste Claude, Hélène Polvèche, Fabien Aubé, Laurent Modolo, Cyril F. Bourgeois, Franck Mortreux, Didier Auboeuf

The paper identifies GC-rich and AT-rich exons with distinct splicing factor dependencies and shows how nucleotide composition bias influences chromatin organization and exon recognition during splicing.

bioRxiv · Apr 11, 2019 · PreprintMolecular Biology