Author

Eliana Melissa Perez-Garcia

University of PittsburghORCID 0000-0002-3185-9649Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:differential expression· 2 Research Focus:gene regulatory network inference· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

Jeongkyung LeeiD· 2 shared Joseph Danvers· 2 shared Ke MaiD· 2 shared Mousumi MoulikiD· 2 shared Ping YangiD· 2 shared Ruya LiuiD· 2 shared Vijay K. YechooriD· 2 shared Vinny NegiiD· 2 shared

Activity by Year

2020-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 44 mutual co-author links

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2 shared papersMolecular Biology

Jeongkyung LeeORCID

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2 papers

Recent·Most cited

Bromodomain protein inhibition protects β-cells from cytokine-induced death and dysfunction via antagonism of NF-κB pathway.

Vinny Negi, Jeongkyung Lee, Varun Mandi, Joseph Danvers, Ruya Liu, Eliana Melissa Perez-Garcia, Feng Li, Rajaganapati Jagannathan, Ping Yang, Domenic Filingeri, Amit Kumar, Ke Ma, Mousumi Moulik, Vijay K. Yechoor

This study shows that BET inhibitor I-BET protects β-cells from cytokine-induced death and dysfunction by inhibiting NF-κB signaling and preserving key β-cell genes.

Cells · Jun 26, 2024Peer-reviewedMolecular Biology

Tead1 reciprocally regulates adult β-cell proliferation and function to maintain glucose homeostasis

Jeongkyung Lee, Ruya Liu, Byung S. Kim, Yiqun Zhang, Feng Li, Rajaganapti Jagannathan, Ping Yang, Vinny Negi, Joseph Danvers, Eliana Melissa Perez-Garcia, Pradip Saha, Omaima M. Sabek, Chad J. Creighton, Cristian Coarfa, Mark O. Huising, , Vijay K. Yechoor

This study shows TEAD1 regulates adult β-cell proliferation and function, maintaining glucose homeostasis by balancing quiescence and mature identity in mice and humans.

bioRxiv · Mar 5, 2020 · PreprintMolecular Biology