Author

Marianne Christina Verhaar

University Medical Center UtrechtORCID 0000-0002-3276-6428Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Genomics· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Assay:bulk RNA-seq· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Research Focus:gene regulatory network inference· 1 Assay:imaging· 1

Frequent Co-Authors

Alain van MiliD· 1 shared Aryan VinkiD· 1 shared Boudewijn M.T. BurgeringiD· 1 shared C. Snijders BlokiD· 1 shared Caroline ChengiD· 1 shared Dorota KurekiD· 1 shared Dries A. M. Feyen· 1 shared Ema Nagyova· 1 shared

Activity by Year

2020-2025 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 29 mutual co-author links

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1 shared paperGenomics

Alain van MilORCID

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2 papers

Recent·Most cited

A Novel Human Distal Tubuloid-On-A-Chip Model For Investigating Sodium And Water Transport Mechanisms

M Bernardi, Emre Dilmen, Dorota Kurek, Henriëtte L. Lanz, Jos Joore, Joost G.J. Hoenderop, Maarten B. Rookmaaker, Marianne Christina Verhaar

This paper presents a human distal tubuloid-on-a-chip model to study sodium and water transport, showing enhanced distal markers, polarized epithelium, and functional sodium transport under flow conditions.

Kidney360 · Sep 17, 2025Peer-reviewedBioengineering

Transcriptional regulation profiling reveals disrupted lipid metabolism in failing hearts with a pathogenic phospholamban mutation

Jiayi Pei, Renée G. C. Maas, Ema Nagyova, Johannes M.I.H. Gho, C. Snijders Blok, Iris van Adrichem, Jorg J. A. Calis, René van Es, Shahrzad Sepehrkhouy, Dries A. M. Feyen, Noortje A. M. van den Dungen, Nico R. Lansu, Nicolaas de Jonge, Hester M. den Ruijter, Manon M. H. Huibers, , Magdaléna Harakaľová

The paper investigates epigenetic and transcriptional changes in PLN R14del cardiomyopathy, identifying disrupted lipid metabolism and altered gene regulation.

bioRxiv · Nov 30, 2020 · PreprintGenomics