Author

Xinzhi Zou

Stanford MedicineORCID 0000-0002-3382-2401Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

Click to filter author papers

Cell Biology· 1 Developmental Biology· 1 Synthetic Biology· 1

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 3 Approach:biophysical modeling· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:drug response / drug discovery· 1 Organism:human· 1 Organism:mouse· 1 Research Focus:perturbation response prediction· 1

Frequent Co-Authors

Michael Z. LiniD· 2 shared Anna Amine· 1 shared Bianxiao CuiiD· 1 shared Bo WangiD· 1 shared C. Yong Kang· 1 shared Chew ChaiiD· 1 shared Chih‐Hao LuiD· 1 shared Cynthia ZhaoiD· 1 shared

Activity by Year

2023-2026 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 17 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

2 shared papersSynthetic Biology

Michael Z. LinORCID

Mutual co-authors in cluster

Author profile →

3 papers

Recent·Most cited

Rewiring oncogenic signaling to RNA vector replication for the treatment of metastatic cancer

Xinzhi Zou, Elizabeth Palafox, Cynthia Zhao, Kevin Thomas Beier, C. Yong Kang, Michael Z. Lin

This paper introduces a RNA vector that replicates specifically in cancer cells with hyperactive HER2, showing lower toxicity and better efficacy against ovarian cancer in mice, and synergizes with chemotherapy.

Nature Biomedical Engineering · Jun 12, 2026Peer-reviewedSynthetic Biology

Membrane Curvature Activates Src kinase and Promotes Metastatic Cancer Cell Survival

Wei Zhang, He You, Xinzhi Zou, Chih‐Hao Lu, Xingyuan Zhang, Anna Amine, Zeinab Jahed, Michael Z. Lin, Bianxiao Cui

This study identifies membrane curvature as a mechanism for Src kinase activation in detached cancer cells, showing that disrupting this process inhibits metastatic survival.

bioRxiv · Mar 4, 2026 · PreprintCell Biology

Ultrafast and long-range coordination of wound responses is essential for whole-body regeneration

Yuhang Fan, Chew Chai, Pengyang Li, Xinzhi Zou, James E. Ferrell, Bo Wang

The paper shows that injury triggers ultrafast Erk signal propagation in planarians, mediated by body-wall muscles, which is essential for regeneration.

Cell · Jul 21, 2023Peer-reviewedDevelopmental Biology