Author

Liangyu Hu

Wageningen University & ResearchORCID 0000-0002-3476-9075Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:mouse· 2 Organism:Drosophila· 1 Research Focus:host-pathogen & immune response· 1 Organism:human· 1

Frequent Co-Authors

Alexia van RinsumiD· 2 shared Deli ZhangiD· 2 shared Jaap KeijeriD· 2 shared Christiane OttiD· 1 shared Jur MassopiD· 1 shared Marcel GiesbersiD· 1 shared Melissa A.E. van de WaliD· 1 shared Melissa Bekkenkamp‐Grovenstein· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 45 mutual co-author links

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2 shared papersPhysiology

Alexia van RinsumORCID

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2 papers

Recent·Most cited

Dual effects of nicotinamide on aging-related arrhythmia: protective at low dose, proarrhythmic at high doses

Liangyu Hu, Yun Hu, Xi Qi, Alexia van Rinsum, Jaap Keijer, Deli Zhang

This study investigates the dual effects of nicotinamide on aging-related arrhythmia, showing protective effects at low doses and proarrhythmic effects at high doses in mouse and Drosophila models.

Journal of the American Heart Association · May 25, 2026Peer-reviewedPhysiology

A novel and robust method for assessing mitochondrial (dys)function in healthy and diseased frozen cardiac tissue

Liangyu Hu, Alexia van Rinsum, Rocco Caliandro, Qi Xi, Shuxiu Fan, Xinyi Jiang, Jur Massop, Melissa Bekkenkamp‐Grovenstein, Christiane Ott, Tilman Grune, Melissa A.E. van de Wal, Werner J.H. Koopman, Marcel Giesbers, Monika M Gladka, Jaap Keijer, Deli Zhang

This paper introduces TSIT, a method to assess mitochondrial function in frozen cardiac tissue, showing comparable results to fresh samples and detecting dysfunction in various mouse models and human samples.

Communications Biology · Aug 19, 2025Peer-reviewedPhysiology