Christiane Ott

Myeloid cell recruitment propels right ventricular dysfunction in HFpEF via sterile inflammation.

This paper shows that myeloid cell recruitment drives right ventricular dysfunction in HFpEF through sterile inflammation in both mice and humans.

The primary cilium controls programmed cell death via its proteasome-regulating function

The paper shows that primary cilia regulate programmed cell death by controlling the proteasomal degradation of MOAP1 through ciliopathy proteins like RPGRIP1L, TCTN1, and CEP290.

A novel and robust method for assessing mitochondrial (dys)function in healthy and diseased frozen cardiac tissue

This paper introduces TSIT, a method to assess mitochondrial function in frozen cardiac tissue, showing comparable results to fresh samples and detecting dysfunction in various mouse models and human samples.