Hui Li

Sex-dependent chronic neurological dysfunction following isoflurane anesthesia and surgery is associated with circulating extracellular vesicle-mediated neuroinflammatory signaling

This study shows that isoflurane anesthesia and surgery cause chronic sex-dependent neurological issues in mice, linked to changes in brain transcriptomes and circulating extracellular vesicles.

Isoflurane and surgery aggravate APOE4-dependent lipid dysregulation and neural dysfunction, leading to neurological impairment in male mice

This study shows that isoflurane anesthesia and surgery worsen lipid dysregulation and neural dysfunction in APOE4 mice, leading to neurological impairments.

Citalopram exhibits immune-dependent anti-tumor effects by modulating C5aR1+ TAMs

This study shows citalopram reduces hepatocellular carcinoma by modulating C5aR1+ tumor-associated macrophages and enhancing CD8+ T cell anti-tumor immunity.

Isoflurane and Surgical Stress Disrupt Fatty Acid and Carbon Metabolism Leading to Cardiomyopathy

This study shows isoflurane and surgical stress cause age-dependent cardiac metabolic and structural changes leading to cardiomyopathy.