Rohan Bhattacharya

This study uses engineered human iPSCs to show that SMAD2 mutations linked to CHD disrupt kidney podocytogenesis and glomerular structure, leading to proteinuria.

The paper reports a novel TRPC6 mutation causing autosomal dominant FSGS and shows that combined Sildenafil and Losartan therapy improves podocyte dysfunction.

This study identifies Ro5-3335 as a chemical that increases HSC clone number and clonal diversity by altering RUNX1 binding partners in zebrafish and mouse models.