Author

Kaira A. Church

The University of Texas MD Anderson Cancer CenterORCID 0000-0002-3982-8476Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Bioengineering· 1 Cell Biology· 1 Immunology· 1 Neuroscience· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:mouse· 3 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:drug response / drug discovery· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:cell-cell communication· 1

Frequent Co-Authors

Raghu KalluriiD· 3 shared Hikaru SugimotoiD· 2 shared Kathleen M. McAndrewsiD· 2 shared Xin LuoiD· 2 shared Aman YarlagaddaiD· 1 shared Andrew S. MendiolaiD· 1 shared Antonios ChronopoulosiD· 1 shared Astrid E. CardonaiD· 1 shared

Activity by Year

2021-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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3 shared papersCell Biology

Raghu KalluriORCID

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Cell BiologybioRxivPreprintAug 11, 2026

Engineered extracellular vesicles targeting BACE1 reduces amyloid beta plaque formation in a genetic mouse model of Alzheimer Disease

Valerie S. Kalluri, Sara P.Y. Che, Meagan Conner…·Raghu Kalluri

This study shows engineered extracellular vesicles delivering BACE1-targeting siRNA reduce amyloid beta plaques in a mouse model of Alzheimer's disease.

DOI 10.64898/2026.08.10.744066

mouseproteomics

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BioengineeringbioRxivPreprintSep 21, 2025

Oncogenic KRAS regulates secretion of extracellular vesicles and surface membrane charge via regulation of phosphatidylserine in pancreatic cancer

Kshipra S. Kapoor, Xin Luo, Kaira A. Church…·Raghu Kalluri

This study develops a microfluidic device to enrich pancreatic cancer-derived extracellular vesicles based on charge, linking KRAS status to EV secretion and surface charge.

1 citation

humanbulk RNA-seq

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ImmunologyJournal of Controlled ReleasePeer-reviewedAug 30, 2024

Development of an engineered extracellular vesicles-based vaccine platform for combined delivery of mRNA and protein to induce functional immunity

Xin Luo, Kathleen M. McAndrews, Kent A. Arian…·Raghu Kalluri

This paper develops an engineered extracellular vesicles-based vaccine platform for combined mRNA and protein delivery, showing tumor regression and immune responses in preclinical models.

30 citations

mousenon-human primate

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NeurosciencebioRxivPreprintJun 6, 2021

Microglial CX3CR1I249/M280 variant limits neurogenesis and remyelination in cuprizone-induced multiple sclerosis model

Andrew S. Mendiola, Kaira A. Church, Sandra M. Cardona…·Astrid E. Cardona

This study shows that the hCX3CR1I249/M280 variant impairs microglial function, reducing neurogenesis and remyelination in a multiple sclerosis model.

DOI 10.1101/2021.06.06.447262

mousebulk RNA-seq

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