Brian P. English

This paper introduces a series of spontaneously blinking dyes with adjustable duty cycles for improved single-molecule localization microscopy in cells and dense structures.

This paper identifies a novel protein transport mechanism involving actin-myosin barriers that direct proteins to the cell's leading edge through fluid flow rather than traditional vesicular or microtubule-based pathways.

This paper introduces a method to create photochromic and blinking fluorophores by combining rhodamine and coumarin dyes, enhancing SMLM labeling options.

The paper uses live-cell single particle imaging to show that RNA polymerase II and Kin28/Cdk7 kinase are required for H2A.Z eviction in yeast, linking it to transcription processes.

This study uses super-resolution imaging to reveal the 3D structure and organizing mechanism of accessible chromatin domains.