Peng Dong

The paper introduces MOSAIC, a multimodal adaptive optical microscope that enables non-invasive imaging across biological scales in live specimens.

This paper introduces a series of spontaneously blinking dyes with adjustable duty cycles for improved single-molecule localization microscopy in cells and dense structures.

The paper investigates how 3D genome organization, specifically through Cohesin, influences gene co-expression in single cells and reveals its role in maintaining long-range chromatin interactions.

This study uses super-resolution imaging to reveal the 3D structure and organizing mechanism of accessible chromatin domains.

This study uses live-cell imaging to show MeCP2 has unique diffusion and chromatin binding kinetics in neurons, distinct from transcription factors and histones.

This study uses live-cell single-molecule imaging to show that TF low-complexity domains form dynamic, selective interaction hubs that stabilize DNA binding and activate transcription.