Author

Tomáš Vomastek

Czech Academy of SciencesORCID 0000-0002-4071-0432Unclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Research Focus:differential expression· 1 Research Focus:gene regulatory network inference· 1 Assay:proteomics· 1 Assay:Ribo-seq· 1

Frequent Co-Authors

Jan BrábekiD· 2 shared Aneta ŠkarkováiD· 1 shared Anna HerrmannováiD· 1 shared Chatpakorn Rassemeena Christiansen· 1 shared Colin AdrainiD· 1 shared Daniel RöseliD· 1 shared Emma BurbridgeiD· 1 shared Farkas KerényiiD· 1 shared

Activity by Year

2024-2026 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCell Biology

Jan BrábekORCID

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2 papers

Recent·Most cited

Rhomboid protease RHBDL2 is a calcium-activated suppressor of EGFR signalling in keratinocytes.

Nicholas Johnson, Jan Dohnálek, Jana Březinová, Josef Čáslavský, Aneta Škarková, Njainday Pulo Jobe, Monika Fliegl, Květa Trávníčková, Emma Burbridge, Vahap Canbay, Chatpakorn Rassemeena Christiansen, Ulrich auf dem Keller, Juraj Lábaj, Olha Fedosieieva, Jan Prochazka, , Kvido Střı́šovský

This study identifies RHBDL2 as a calcium-activated rhomboid protease that suppresses EGFR signaling in keratinocytes by shedding its ectodomain, thereby limiting cell migration and invasion.

Cellular and Molecular Life Sciences · Aug 17, 2026Peer-reviewedCell Biology

Perturbations in eIF3 subunit stoichiometry alter expression of ribosomal proteins and key components of the MAPK signaling pathways.

Anna Herrmannová, Jan Jelı́nek, Klára Pospíšilová, Farkas Kerényi, Tomáš Vomastek, Kathleen Watt, Jan Brábek, Mahabub Pasha Mohammad, Susan Wagner, Ivan Topisirović, Leoš Shivaya Valášek

The paper shows that altering eIF3 subunit levels affects the translatome, particularly impacting MAPK signaling and ribosomal protein expression in HeLa cells.

eLife · Nov 4, 2024Peer-reviewedMolecular Biology