Marrow-mimicry MEW scaffolds recapitulate erythroblastic islands for high-density cRBC biomanufacturing
Gloria Astrid Nausa Galeano, Susana Alexandra Costa Maia, Naomi C. Paxton, Kavita Bisht, Yoel Garcia Marin, Ryan McKinnon, Chloe M. de Nys, Keyu Tao, Lorenzo Moroni, Justin John Cooper-White, Maria Ann Woodruff, Rose Ann Franco, Ashley R. Murphy, Rebecca E. Griffiths, Mark C. Allenby
This study develops marrow-mimic scaffolds that enhance cRBC production by supporting macrophage-erythroblast interactions in high-density cultures.
bioRxiv · Oct 27, 2026 · PreprintBioengineering