Noelia Rodríguez-Iglesias

A bottom-up approach identifies the antipsychotic and antineoplastic trifluoperazine and the ribose derivative deoxytubercidin as novel microglial phagocytosis inhibitors.

The paper identifies two compounds, trifluoperazine and deoxytubercidin, as novel microglial phagocytosis inhibitors using high-throughput screening and in vivo validation.

Microglia and meningeal macrophages depletion delay the onset of experimental autoimmune encephalomyelitis

The paper shows that depleting microglia and meningeal macrophages delays the onset of EAE by reducing antigen presentation and T cell reactivation.

VolumesJ: A new method and tool for volumetric estimation of brain structures after serial sectioning.

The paper introduces a new volumetric estimation method (TCS) and a tool (VolumestJ) for analyzing brain structure volumes from tissue sections, showing improved accuracy over the classical Cavalieris method.