Tim Ullrich Magnus

This study shows that enhancing CD73 in mouse brain endothelial cells reduces infarct volume and mortality after stroke by promoting adenosine production and modulating neuroinflammation.

This study identifies Aβ42-carrying extracellular vesicles in plasma as biomarkers associated with neurodegeneration and neuroinflammation in Alzheimer's disease.

The paper shows that short-term microglia depletion after stroke improves motor recovery and changes brain connectivity.

This paper develops and validates an optimized workflow for isolating and characterizing extracellular vesicle subsets from diverse sources using FACS and imaging techniques.

This study shows that extracellular vesicles from cortical neurons alter spontaneous activity in recipient neurons by increasing postsynaptic potential amplitude.

This study identifies ADAM10-mediated shedding of human PrP at Y226 and shows sPrP associates with misfolded protein aggregates in neurodegenerative diseases.

This study identifies cystatin C as a neuroprotective protein upregulated after stroke and shows that delivering it via brain-derived extracellular vesicles improves synaptic preservation in vitro and in vivo.

The paper shows that depleting microglia and meningeal macrophages delays the onset of EAE by reducing antigen presentation and T cell reactivation.

The paper shows that changes in aperiodic spectral exponents in ECoG data from mice with sensory cortical stroke correlate with fine motor recovery.

This paper reports a preclinical randomized trial showing that anti-IL-17A treatment reduces infarct volume in a mouse stroke model.

This study characterizes brain-derived extracellular vesicles (sEVs) in mice under normal and post-stroke conditions, showing increased PrP and PrP-C1 content and altered cellular uptake.

This study shows Mincle plays a key role in ischemic CNS injury but not traumatic injury or peripheral ischemia, with functional improvements in Mincle-deficient mice.