Jessica Avila Lopez

In vivo inhibition of stearoyl-CoA desaturase modulates the hippocampal fatty acid profile and restores density of dendritic spines in the aggressive 5xFAD model of Alzheimer s disease

This study shows that inhibiting SCD improves fatty acid profiles and restores dendritic spine density in a 5xFAD Alzheimer's model.

More is better: A simple antibody-based strategy for recovering all major mouse brain cell types from multiplexed single-cell RNAseq samples.

The paper introduces a multiplexing strategy for scRNA-seq of adult mouse brain samples using anti-Thy1.2 antibodies and secondary oligonucleotide-labeled antibodies, enabling pooled sequencing with efficient demultiplexing and cost reduction.

Impact of in vivo cyclic reprogramming on the choroid plexus

This study investigates the effects of cyclic in vivo OSKM reprogramming on the choroid plexus, finding limited transcriptomic changes but increased NKCC1 expression and minor morphological alterations.