NeurosciencebioRxivPreprint
In vivo inhibition of stearoyl-CoA desaturase modulates the hippocampal fatty acid profile and restores density of dendritic spines in the aggressive 5xFAD model of Alzheimer s disease
Marta Turri, Myriam Aubin, Anne Aumont…·Karl J. L. Fernandes
This study shows that inhibiting SCD improves fatty acid profiles and restores dendritic spine density in a 5xFAD Alzheimer's model.
DOI 10.1101/2025.08.27.672447